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社评“男Ji大巴从裤子里放出来”-梳理天下新闻

专家呼吁:男Ji大巴从裤子里放出来异基因造血干细胞移植患者慢性排异管理“早”字当先

来源: 中国网科技
2024-12-25 02:00:36

最佳回答

“男Ji大巴从裤子里放出来”专家呼吁:男Ji大巴从裤子里放出来异基因造血干细胞移植患者慢性排异管理“早”字当先

  近年男Ji大巴从裤子里放出来来,中国异基因造血干细胞移植男Ji大巴从裤子里放出来(allo-HSCT)年增长量不低。在移植体量和疗效逐步提高的同时,术后常见并发症,如cGVHD(俗称“男Ji大巴从裤子里放出来慢性排异”)正成为移植后患者面临的“次生灾害”。30%—70%异基因造血干细胞移植患者术后都存在发生cGVHD的风险。该疾病会累及皮肤、眼睛、口腔、关节等多个组织器官,严重影响患者生活质量,是异基因造血干细胞移植患者晚期非复发性死亡的首要原因。

  12月23日,国家血液系统疾病临床医学研究中心常务副主任、中华医学会血液学分会主任委员吴德沛教授指出,目前许多cGVHD患者在术后管理中更多聚焦于移植的原发病,往往容易忽视并发症症状,需要进一步提升管理意识。其次,针对纤维化的核心问题也十分关键。

  吴德沛认为, cGVHD的治疗目标一方面需要建立免疫耐受以维持免疫稳态,进而有效预防、减少纤维化,另一方面对于发生纤维化的组织和器官,希望能够有效的直接逆转纤维化,因此免疫稳态和逆转纤维化是cGVHD的治疗目标和核心,选择针对性治疗方式尤为关键。

  (陈静 视频制作 乐小敏)

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