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解惑“把男生的坤坤放进女生的坤坤里”-环球时报

港中大发现把男生的坤坤放进女生的坤坤里治疗子宫内膜异位症的新靶点及药物

来源: 郑州日报
2025-01-15 06:21:08

最佳回答

“把男生的坤坤放进女生的坤坤里”港中大发现把男生的坤坤放进女生的坤坤里治疗子宫内膜异位症的新靶点及药物

  中新把男生的坤坤放进女生的坤坤里网香港1月14日电 (记者 把男生的坤坤放进女生的坤坤里韩星童)香港中文大学(港中大)医学院14日召开记者会公布,研究团队发现两个治疗子宫内膜异位症的新靶点,并发现一种现有药物可用于治疗子宫内膜异位症。

  据介绍,子宫内膜异位症指子宫内膜组织生长在子宫腔与子宫肌层以外的把男生的坤坤放进女生的坤坤里部位,是妇科的常见病及多发病。这种疾病多发于育龄期女性,发病率为10%至15%,可带来严重痛经、急腹痛、不孕等症状,极大影响患者的身心健康和生活质量。

  研究团队利用人工智能系统,针对异位内膜组织的表达基因大数据进行分析,寻找可以通过药物抑制的新治疗靶点,成功发现一种调节免疫及抑制炎症过程的“环腺苷酸结合蛋白2”(GBP2)和负责细胞增殖和生物讯号传导的“造血细胞激酶”(HCK),具有治疗子宫内膜异位症的潜力。

  同时,研究团队也发现,治疗干眼症的非类固醇抗炎药物整合素抑制剂有助抑制异位内膜组织的生长,可以“旧药新用”,可成为子宫内膜异位症的新治疗方案。

  领导该项研究的港中大医学院妇产科学系教研室主任及教授黄志超表示,确定GBP2和HCK作为新治疗靶点,有助研究团队理解子宫内膜异位症的疾病发展机制,从而计划更精准及有效的治疗策略。GBP2和HCK在人体子宫内膜异位样本中的基因表达更强,显示它们与子宫内膜异位症有强烈的关联性。

  港中大医学院妇产科学系系主任及临床教授潘昭颐表示,期望研究成果有助治疗子宫内膜异位症,改善患者的生活质量。(完)

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