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解惑“2023管家婆资料正版大全澳门”-知识课堂

肢端肥大症2023管家婆资料正版大全澳门起病隐匿 专家:出现手脚增大勿忽视

来源: 河南日报
2024-11-16 07:56:03

最佳回答

“2023管家婆资料正版大全澳门”肢端肥大症2023管家婆资料正版大全澳门起病隐匿 专家:出现手脚增大勿忽视

  中新2023管家婆资料正版大全澳门网义乌11月14日电(张煜2023管家婆资料正版大全澳门欢)“许久没见的老朋友,说我和以前完全是两个人。”近日,义乌市民姚阿姨从朋友口中注意到自己的异常,不2023管家婆资料正版大全澳门知不觉间,她的面容变成了大鼻子、大嘴巴和宽下颚,鞋码也从37码变成了40码……随后姚阿姨在医院确诊为肢端肥大症,病因是垂体生长激素肿瘤。浙大四院国际医疗部副主任兼内分泌科副主任杨甜提醒,民众如出现面容改变、手脚增大等症状,可能是患上了肢端肥大症,应及时就医。

专家对姚阿姨进行会诊。浙大四院供图

  近五年来,患者姚阿姨每天早起时总感觉手指僵硬,伸展不利索,整天还感觉昏昏沉沉,睡不够、睡不饱,有时候还会头晕,但是体检的脑部检查并没有发现异常。最近,她的两个膝关节也开始疼痛。来到浙大四院内分泌科就诊后,姚阿姨正式确诊为肢端肥大症,病因是垂体生长激素肿瘤。

  杨甜介绍,垂体大小介于绿豆和黄豆之间,是人内分泌系统的“司令官”。垂体瘤是引起肢端肥大症的主要原因,这是因为垂体生长激素肿瘤会长期过量分泌生长激素,进而引起全身软组织、骨和软骨过度增生。

  “生长激素分泌过多主要发生在青少年期,会引起骨骼的纵向生长,称之为巨人症;如果发生在成人时期,则引起骨骼的横向生长,具体表现包括手足增大、鼻翼增宽、口唇肥厚,到后期可以表现为头形增长、下颌前突、牙齿稀疏,最后整个相貌发生改变,称之为肢端肥大症。”杨甜说。

  专家表示,除了外貌骨关节的改变,该病症还影响全身其他系统,高血压、糖尿病、心脑血管疾病风险增加,肿瘤风险也会增高,其中骨肿瘤风险是正常人的13.8倍。

  此次姚阿姨的垂体瘤位置紧贴海绵窦,把正常的垂体挤压变形得厉害。经过浙大四院垂体多学科团队三位专家的联合诊疗和评估,其一致建议患者进行手术治疗。术中,姚阿姨的垂体肿瘤顺利切除,正常的垂体得以完整保留。术后第4天患者就顺利出院。

  专家称,垂体瘤多数属于良性肿瘤,绝大多数的生长激素型垂体瘤经过合理治疗后,生长激素水平可以得到有效缓解,高生长激素导致的全身危害可以改善,预期寿命可以显著延长。但由于肢端肥大症起病很隐匿,发展很缓慢,外观出现变化需要很多年,所以很容易被忽略,从发病到诊断病程平均10年。

  “由于发展缓慢,很多人往往不能及时发现外貌变化,很大一部分患者是在出现了高血压、夜间睡眠打鼾等肢端肥大症的并发症后前来就医才发现。我们建议有类似症状的患者及时到医院就诊。”杨甜说。(完)

发布于:吉林长春九台市
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